How to Make a Multi-Panel Figure

A step-by-step guide to creating multi-panel scientific figures for publication. Panel labels, alignment, spacing, and journal-width presets.

Step 1: Prepare Individual Panels

Create each panel as a separate high-resolution image. Ensure consistent font size, color palette, and axis styling across all panels.

Checklist: ✓ Same font family ✓ Same font size for axes ✓ Same color palette ✓ Consistent line weights ✓ Same background color

Step 2: Choose Figure Width

Select single-column or double-column width based on your journal and panel complexity.

JournalSingle ColumnDouble Column
Nature89 mm183 mm
Cell85 mm174 mm
Science84 mm174 mm
PNAS88 mm180 mm

Step 3: Arrange Panels in Layout

Place panels in a logical reading order. Group related panels together.

A
B
C
D

Standard 2×2 layout for four panels. Adjust based on panel sizes and aspect ratios.

Step 4: Add Panel Labels

Add uppercase letters (A, B, C, D) in the top-left corner of each panel. Use a bold, consistent font. FigureGuild automatically applies panel labels in a journal-compliant font.

Recommended: Arial or Helvetica, bold, 10–12 pt, black or dark gray color. Place 2–3 mm from the top-left corner of the panel border.

Step 5: Set Consistent Spacing

Apply 3–5 mm spacing between panels. Consistent spacing is critical for a professional appearance.

Tip: Use the same spacing between all panels, both horizontally and vertically. Uneven spacing makes the figure look unprofessional.

Step 6: Export at Journal DPI

Export at 300 DPI minimum. Use TIFF for raster images or PDF for vector graphics.

Tip: Use FigureGuild’s one-click journal presets to export at the exact dimensions, DPI, and color mode for your target journal.

Frequently Asked Questions

What is a multi-panel figure?

A multi-panel figure is a single image composed of multiple sub-figures (panels) labeled A, B, C, D, etc. Each panel shows a different experiment, data view, or magnification. Multi-panel figures are standard in scientific publications.

How do I label panels in a multi-panel figure?

Use uppercase letters (A, B, C, D) in a bold, consistent font. Place labels in the top-left corner of each panel. Maintain consistent font size and weight across all panels. FigureGuild automatically applies panel labels in a journal-compliant font.

What spacing should I use between panels?

Use 3–5 mm spacing between panels. Consistent spacing is critical for a professional appearance. FigureGuild’s multi-panel tool enforces uniform spacing automatically.

What width should a multi-panel figure be?

Single-column figures are 84–90 mm wide. Double-column figures are 174–183 mm wide. Check your target journal’s exact requirements. FigureGuild applies these dimensions with one-click journal presets.

Related Pages

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